More from the Sister Study

In the March 17, 2009 issue of Life Extension Update, we reported the finding from the Sister Study, a cohort of healthy sisters of breast cancer patients, of a beneficial association between multivitamin use and telomere length, a biomarker of aging. Telomeres, which are repeating DNA sequences that cap the ends of chromosomes, shorten with increased cellular aging.

In articles published in the February and March, 2009 issues of the journal Cancer Epidemiology Biomarkers and Prevention, further findings from the Sister Study concerning the impact of lifestyle on telomere length were revealed.

In the February, 2009 issue, Christine Parks, PhD, of the National Institute of Environmental Health Sciences of the National Institutes of Health (NIH) and her associates evaluated the effect of stress on telomere length in 647 Sister Study participants. Telomere length in DNA from blood samples was measured, and stress hormone levels in urine were assessed. Questionnaires completed by the subjects provided information on perceived stress levels.

Study participants, on average, reported low stress levels. “Even so, women who reported above-average stress had somewhat shorter telomeres, but the difference in telomere length was most striking when we looked at the relationship between perceived stress and telomere length among women with the highest levels of stress hormones,” Dr Parks observed. “Among women with both higher perceived stress and elevated levels of the stress hormone epinephrine, the difference in telomere length was equivalent to or greater than the effects of being obese, smoking or 10 years of aging.”

In the report that appeared in the March, 2009 issue of the journal, the effect of past and current body mass index (BMI) on telomere length was examined. Sister Study participants whose BMI categorized them as overweight or obese before or during their thirties and whose weight status was maintained were found to have shorter telomeres compared to subjects who became overweight at an older age. “This suggests that duration of obesity may be more important than weight change per se, although other measures of overweight and obesity were also important,” stated lead author Sangmi Kim, PhD, also of the National Institute of Environmental Health Sciences. “Our results support the hypothesis that obesity accelerates the aging process”.

“We anticipate a wealth of information to come out of the Sister Study,” predicted Dale Sandler, PhD, chief of the Epidemiology Branch at the National Institute of Environmental Health Sciences and principal investigator of the Sister Study. “Not only do we hope to find out more about the environmental and genetic factors that might lead to breast cancer, we also want to learn more about how factors such as stress, diet and exercise might impact cancer and other disease risks.”

“Together these two studies reinforce the need to start a healthy lifestyle early and maintain it,” National Institute of Environmental Health Sciences director Linda Birnbaum, PhD, concluded. “These papers remind us that there are things people can do to modify their behavior and live healthier lives, such as maintain a healthy weight and cultivate healthy responses to stress.”

First Steps To Fixing A Broken Relationship And Getting Your Ex Back

Have you just gone through a break up and wondering how to get your Ex back? Most people who have gone through a break up work on moving on from the relationship but in many cases it is possible to work towards getting back with an Ex. If you are prepared to put in some work rather than play a victim role, it is possible to rekindle a relationship.

Relationship break ups happen for many reasons, it could be a single event or over time due to behaviours your Ex could not deal with any longer. Taking some time to examine where the relationship started to go wrong helps you to discover how to deal with the specific incidents should they come up again. You can get your Ex back but you need to want to make the relationship work on a long term basis and to do that you need to understand what went wrong the first time around.

This period of introspection does not mean you should beat yourself up and get depressed. We can not change the past but we can learn from mistakes we made during and use the knowledge to help reconcile a broken relationship.

You should also work on your self confidence and self esteem. After a relationship break up it is natural to feel you can not live without the ex partner and spiral into negative behaviours and attitudes. If your Ex sees you as desperate or needy they likely will not be open to the possibility of renewing the relationship. Do not hide away from the world, go out, socialise and network. By appearing confident and able to cope on your own you will have a better chance of getting back together with your Ex.

Never try and make your Ex jealous or try to get back at your Ex. These are the worst things you can do as it will just confirm to your Ex that the relationship is best ended and that they should move on. You do not want to push them further away and encourage them to move on completely if you want to get back together with your Ex.

Fixing a broken relationship will not happen overnight, but by taking these first steps you will be well on the way to winning back your love.

*Examine the reasons why the relationship ended.
*Learn from any mistakes.
*Do not beat yourself up!
*Stay confident.
*Keep socialising, get out and have fun.
*Do not try and make your Ex jealous
*Do not try to get back at your Ex.

Letting everyone – including your Ex, know how strong and self confident you are and that you can cope well outside of a relationship are the first steps to inspiring your Ex into get back together with you.

Little Thoughts To Enhance Your Love Life, Relationship And Marriage

I have some thoughts to share with you which may be had never struck your mind. Now that you are in love, you are suffering from that love pain or you are enjoying that bliss you can realize how simple and logic things can make your relationship better. Some little explanations can help you understand many easy matters which you can apply in your life.

People get crazy when they are in love but all the craziness disappears when they are married. They experience troubles in their marriages and therefore their passion fades with time. But its not always the case; you must have the gut to preserve your marriage by seeking appropriate help.

Sometimes love never dies a natural death. It dies because we don’t know how to replenish its source. It dies of blindness and errors and betrayals. It dies of illness and wounds; it dies of weariness, of withering, of tarnishing. You people who are in love, married or engaged in a relationship, dont let misunderstandings kill your love life. Refill its sources with proper help. Dont cheat on your partner, apologize for every mistake you do, for every pain you give to the one you love and fix your relationship troubles to save your love life.

In order to have a successful marriage or love life, having the same goals are the keys. If you have the same goals, you will both work together to realize them. Otherwise each one of you will have separate paths.

Compromise is the base for a successful marriage or relationship. If you try to compromise, you will notice having a healthy marriage is not a dream. But this does not mean that only partner must adjust, it must be balanced. Both partners must put in the same effort.

Top Strategies To Find College Scholarships

When considering where to go to college, many students first consider the availability of college scholarships. There are many sources of college scholarships, and here are four top strategies for finding these money-saving scholarships.

1. Financial Aid Office
All colleges have a financial aid office, and this should be the first place prospective students should look for funding. Completing paperwork on time is very important, since college funding may run out. In addition to federal funding, many financial aid offices keep databases of independent scholarships, which not many students use.

2. College Department
All college students have to choose a major, and many students find a college by major. College majors are organized into departments and then into colleges, such as a Department of English within a College of Liberal Arts and Sciences. Many of these departments and college may award college scholarships directly to students in their programs. Once prospective students find a college by major , they should contact their academic program to ask about scholarship options.

3. Family Members Employers
Many prospective students reach out to family members for advice on where to go to college ; some will even say, Help me find a college . Once students have found a college to attend, many do not realize that they can reach out to their family members again for help in finding college scholarships. Many employers offer college scholarships to students who are related to their employees. A prospective college students plea of help me find a college should be followed by help me find a college scholarship.

4. Just Ask
One of the best strategies for finding college scholarship is to always ask. Contact local businesses and nonprofit organizations to see if they offer scholarships. Students can ask about funding through organizations that they are a member of. Also, students can ask financial aid offices and college departments for more funding if the initial funding is not enough.

Titlekey Sorting Out A Damaged Relationship By Evaluating Your Self

Blaming or going into denial will cause the relationship to slowly get even worse. Believing we had nothing to accomplish with the romantic relationship becoming broken seems easier, but there are lots of reasons and issues that aren’t resolved as to how it happened.

You need to begin searching at yourself to find out what went incorrect instead of shrugging it off. Know what went wrong and learn on how to repair it prior to it gets worse.

To get the right assist and perspective from the situation, its best that you study the ebook, ‘How to obtain your Lover Back’. Honesty is really important when it comes to asking yourself the questions.

No one in a relationship is ideal, so stop pretending points were. You have to admit your errors in order to being fixing the broken relationship. You should answer them for yourself.

Are you getting the relationship seriously, may be the first question the e-book asks. You should believe lengthy and difficult about it. Do your actions match your intentions? The solution lies in whether or not you are taking the time to find out and dig deeper by reading, How to Fix a Damaged Romantic relationship. Move on if you aren’t significant about fixing the broken romantic relationship. To shed light on how you have been behaving in a relationship, the e-book offers much more queries that will help.

“The Ex-Recovery Interactive Journal’ offers advice via the difficult emotions and thoughts that you may be dealing with. Understanding how to fix a broken relation is an exercise which will assist you to along with your actions. The journal helps you by giving you quizzes to determine where the problem is in the relationship.

Do you long for the answers to the question on the concern of how to fix a relationship?

Elle and Be The Best Wedding Cinematographer

Weddings are an auspicious occasion that is the first step of a beautiful relationship that lasts forever. It is one of the happiest occasions of not only the bride and the groom but both the families as this event unites two lovely souls. Be it the bride or the groom, both of them looks their best on this auspicious day. Many beautiful moments are created during a wedding and a wedding is incomplete without good wedding photographers as they have a great role to play in making your wedding memories priceless. A good photographer will capture all the beautiful moments from the best possible angles so that the pictures look natural. You would always want your wedding memories to stay with your forever. And this would only be possible when you hire the services of Elle and Be.

They specialise in wedding cinematography and their years of experience in this field have helped them to make a name for themselves. From clicking the perfect wedding pictures to creating videos, they are your best choice as they are sure to create master pieces so that you relive these lovely moments whenever you want to. They not only click pictures and make videos but they also customise these videos to make them more romantic so that you fall in love with your spouse all over again each time you see these wedding videos of yours. In short, Elle and Be create magic that no other wedding photographer do. They capture all the priceless moments so that you enjoy these for a lifetime.

Their professional attitude and creative wedding photography ideas have helped to win the confidence of many esteemed clients for Toronto event photography. They also specialise in South Asian Wedding Photography Toronto and so if you want them to create magic with their cameras log on to ellebefilms.com for further details. >

Study Shows Marijuana Prevents Seizures in Epileptics

Seizure”, a journal produced by the British Epilepsy Association ,indicates that one of the active ingredients in marijuana, cannabidiol, significantly reduces seizure risk in epileptics.

There is increasing evidence that among the many diseases helped by medicinal marijuana is epilepsy. Historically, epilepsy has been very difficult to treat. Part of the problem is that sixty percent of suffers don’t know the cause. Unless there was some obvious head trauma, the cause of epilepsy goes undiagnosed. Currently treatment options are limited. There are a handful of drugs that help prevent the seizures associated with epilepsy. These include: Tegretol, Dilantin, Klonopin, Mysoline and Zarontin. Unfortunately, all of these drugs come with horrible side effects. Potential for conditions such as anemia, headaches, hair loss, depression, psychosis, and impotence cause many suffers to reject pharmaceutical treatment for their illness. Many users of these drugs report a negative lifestyle change compared to untreated epilepsy. Some of them even had to use drug detoxes to save themselves from drug poisoning The most common non-pharmaceutical treatment is known as the Ketogenic Diet. The Ketogenic Diet is a treatment that was popular throughout the early twentieth century, and is making a come back. The diet is similar to Atkins in that it is high fat, low carbohydrates. This causes the body to go into starvation mode which seems to reduce the amount of seizures. For obvious reasons starving epileptic children is not ideal but is experiencing resurgence due to the side effects of epileptic drugs. That is why new evidence that marijuana can be as effective as pharmaceuticals, without the side effects is so exciting. The two main compounds that researchers have identified are Cannabidiol and GWP42006. These two compounds that are found in marijuana have been proven to help epilepsy in animals. Unfortunately, human testing of this treatment could take as much as three years to receive government approval. A recent study has shown that 21% of epilepsy suffers have taken it upon themselves to treat their symptoms with marijuana. Almost all will attest to its beneficial properties. The government and the drug war turn sick people looking for treatment into criminals. It is unconscionable and inhuman. Dr. Ben Whelley lead the research team studying marijuana’s effects on epileptic animals. He believes that the reason for government denial of medical marijuana is caused by -a stigma associated with cannabis that comes our from the 60s and 70s associated with recreational use, so people have tended not to look at its medical benefits.-

Online Dating Sites – The Future Of Dating Introductions

Fasten your seatbelts, you might be in for a roller-coaster ride! Online dating sites have arrived and some web surfing may be required….

Online dating sites provide singletons with a modern way to connect with potential partners in their local areas and all across the world. These websites are so simple to use, that people can quickly register a profile and start reaping the benefits.

You might well be over-whelmed by the huge quantity of online dating sites around today. Every year, more are appearing and the amount of members are increasing considerably. You’ll be pleased to hear that lots of long-term relationships have resulted from random introductions on online dating sites.

Recently, many people were suspicious about online dating sites. Because of the nature of the web, it’s simple to upload whatever data you want with virtually no safeguards present to determine whether the data is correct. However, this attitude is gradually changing.

Frequently, you hear anecdotes about successful relationships that have blossomed from introductions through online dating sites. This success is largely owed to the compatibility and personality tests that these websites offer to their members. The sites genuinely provide a fantastic way to look for possible dates. You just type in the personality traits you are seeking and initiate the search function, which gives you a list of potential matches.

Signing up to many online dating sites is complimentary and you’re not under any obligation to purchase any of the services on offer. It’s a simple and fun method to hook up with many new people from all corners of the world. The internet, undoubtedly, offers the best and most effective way to learn about new people and cultures.

The online dating sites of today offer facilities for you to upload photos and provide extra details about yourself. They also permit you to specify the type of date you are searching for. By using this function, you can look for people based on education, location, weight, height, ethnic origin, hair colour, eye colour, interests and hobbies.

So, no longer do you have to limit yourself to choosing your partner from your local dating pool, you can now look far and wide for your perfect date from the convenience of your living room. This is among the greatest benefits of online dating sites. Without having to leave your house, you can link up with a wide range of different people.

Prepare yourself to chat to people from every walk of life, and be mindful that not everyone you talk to will necessarily be the type of person you might normally socialise with. Don’t forget that online dating sites are used by everyone, so approach every new relationship with a liberal mind and a positive outlook.

Most importantly, always remember to exercise some sensible precaution by not divulging any personal details, like your home phone number or address, until you are totally comfortable with the idea of doing this.

Dinorama – Entertaining Dino Education for Your Kid

If you are looking for a decent education software for the kid you can look on iTunes store to get the best app for your smartphone and tablet. There is lots of title out there that offer enjoyable and entertaining education for your kid for instance alphabet understanding, animal learning, and much more. one of those applications is Dinorama, Dinorama is a fun as well as interesting application to instruct your kid about the great creature in the past, dinosaur. Having cute graphic and straightforward control Dinorama surely has plenty to give. Let’s find out what this application is offering under.

Feature

Quite simply, the game is a time management skills game where being a park owner you have to feed, make habitat for dinosaur, selling popcorn, and even more. Although there are numerous thing to complete, this game is not hard to learn and quite addicting for some part. Your kid can learn to manage a park as well as understand the financial as well because they must take care of the snacks selling, feed fee, and ticket. Next to handle all the stuff that’s must be carried out your park, you’ll be able to hire an worker to assist you run the park effectively.

This app really train your kid the way to be a young entrepreneur, there are lots of random circumstance that occurs during the day such as rainstorm that make the ticket sale change, crop disaster make the food cost high, and even piggy bank to make them fascinated. Those random circumstance could make your kids think and study from what they’ve to do in order to make the park continue running. Near the management, your children can also play of course together with the dinosaur by providing them with food and even touch them while using touch screen.

For that dinosaur, you are able to breed it with 8 different colors in every kinds. Not just that could make your park much more colorful, you can also have several dinosaurs with all your favourite color. There are numerous mini games that you could have fun with like finding lost items, getting a tour guide to assist you see the dinosaur, and even help your visitor found their most favorite dinosaur. Even though the day seems okay, sometime your park requires some servicing and you have to do the repair by yourself. This application really offer lots of things to find out and to carry out for your kids, you’ll be able to download this game on iTunes for free.

Rendy Rembana is one of the author at Paseban Portal. Covering information, review and tips about Mobile Apps and Games